Publications

2024

54. Reversible Disulfide Bond Cross-Links as Tunable Levers of Phase Separation in Designer Biomolecular Condensates

Mondal, M.; Jankoski, P.; Lee, L.; Dinakarapandian, D.; Chiu, T.; Swetman, W.; Wu, H.; Paravastu, A.; Clemons, T.; Rangachari, V. J Am Chem Soc 2024. DOI: 10.1021/jacs.4c09557.

53. Hybrid Bonding Bottlebrush Polymers Grafted from a Supramolecular Polymer Backbone

Clemons, T.; Egner, S.; Grzybek, J.; Roan, J.; Sai, H.; Yang, Y.; Syrgiannis, Z.; Sun, H.; Palmer, L.; Gianneschi, N.; et al. J Am Chem Soc 2024, 146 (23), pp. 16085-16096. DOI: https://doi.org/10.1021/jacs.4c03320.

52. Single-Cell Coating with Biomimetic Extracellular Nanofiber Matrices

Lee, S.; Carrow, J. K.; Fraser, L. A.; Yan, J.; Jeyamogan, S.; Sambandam, Y.; Clemons, T. D.; Kolberg-Edelbrock, A. N.; He, J.; Mathew, J.; et al. Acta Biomater 2024.

2023

51. Enhanced Neuron Growth and Electrical Activity by a Supramolecular Netrin-1 Mimetic Nanofiber

Smith, C. S.; Alvarez, Z.; Qiu, R.; Sasselli, I. R.; Clemons, T.; Ortega, J. A.; Vilela-Picos, M.; Wellman, H.; Kiskinis, E.; Stupp, S. I. ACS Nano 2023.

50. Indocyanine Green-Glycogen Conjugates for Near-Infrared-Triggered Photothermal Cancer Therapy

Shirinichi, F.; Karkera, C.; Ibrahim, T.; Khan, H.; Clemons, T.*; Senejani, A. G.; Sun, H. Macromol Chem Phys 2023.

49. Supramolecular Nanofibers Block SARS-CoV-2 Entry into Human Host Cells

Qiu, R.; Chen, F.; Alvarez, Z.; Clemons, T. D.; Biswas, S.; Karver, M. R.; Takata, N.; Sai, H.; Peng, H.; Weigand, S.; et al. ACS Appl Mater Interfaces 2023.

48. CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology

Ortega, J. A.; Sasselli, I. R.; Boccitto, M.; Fleming, A. C.; Fortuna, T. R.; Li, Y.; Sato, K.; Clemons, T. D.; McKenna, E. D.; Nguyen, T. P.; et al. Science Advances 2023, 9 (45), eadf7997.

47. Role of supramolecular polymers in photo-actuation of spiropyran hydrogels

Li, C.; Xiong, Q.; Clemons, T. D.; Sai, H.; Yang, Y.; Hussain Sangji, M.; Iscen, A.; Palmer, L. C.; Schatz, G. C.; Stupp, S. I. Chemical Science 2023, 14 (22), 6095-6104.

46. De novo amyloid peptides with subtle sequence variations differ in their self-assembly and nanomechanical properties

Abernathy, H. G.; Saha, J.; Kemp, L. K.; Wadhwani, P.; Clemons, T. D.; Morgan, S. E.; Rangachari, V. Soft Matter 2023, 19 (27), 5150-5159.

2022

45. Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms

Ledford, B. T.; Akerman, A. W.; Sun, K.; Gillis, D. C.; Weiss, J. M.; Vang, J.; Willcox, S.; Clemons, T. D.; Sai, H.; Qiu, R.; et al. ACS Nano 2022.

44. A Perspective on the History and Current Opportunities of Aqueous RAFT Polymerization

Fortenberry, A. W.; Jankoski, P. E.; Stacy, E. K.; McCormick, C. L.; Smith, A. E.; Clemons, T. D.* Macromolecular Rapid Communications 2022.

43. Machine learning makes magnificent macromolecules for medicine

Cunitz, V.; Stacy, E.; Jankoski, P.; Clemons, T*. Matter 2022, 5 (8), 2558-2561.

42. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis

Chaudhari, N.; Findlay, A. D.; Stevenson, A. W.; Clemons, T. D.; Yao, Y.; Joshi, A.; Sayar, S.; Wallace, G.; Rea, S.; Toshniwal, P.; et al. Nature Communications 2022, 13 (1), 5555.

2021

41. Development of novel nanofibers targeted to smoke-injured lungs

Mercel, A. I., Marulanda, K., Gillis, D. C., Sun, K., Clemons, T. D., Willcox, S., Griffith, J., Peters, E. B., Karver, M. R., Tsihlis, N. D., Maile, R., Stupp, S. I., Kibbe, M. R. Biomaterials 2021, 274, 120862.

40. Intravenous Delivery of Lung-Targeted Nanofibers for Pulmonary Hypertension in Mice

Marulanda, K.,  Mercel, A.,  Gillis, D. C.,  Sun, K., Gambarian, M.,  Roark, J.,  Weiss, J.,  Tsihlis, N. D.,  Karver, M. R.,  Centeno, S. R.,  Peters, E. B.,  Clemons, T. D.,  Stupp, S. I.,  McLean, S. E., Kibbe, M. R. . Advanced Healthcare Materials 2021, e2100302.

39. Allomelanin: A Biopolymer of Intrinsic Microporosity

McCallum, N. C., Son, F. A., Clemons, T. D., Weigand, S. J., Gnanasekaran, K., Battistella, C., Barnes, B. E., Abeyratne-Perera, H., Siwicka, Z. E., Forman, C. J., Zhou, X., Moore, M. H., Savin, D. A., Stupp, S. I., Wang, Z., Vora, G. J., Johnson, B. J., Farha, O. K., Gianneschi, N. C. J Am Chem Soc 2021.

38. Self‐Assembling Nanofibers Inhibit Inflammation in a Murine Model of Crohn's‐Disease‐Like Ileitis

Bury, M. I.,  Fuller, N. J.,  Clemons, T. D., Sturm, R. M., Morrison, C. D., Lisy-Snow, D. C., Nolan, B. G.,  Tarczynski, C., Ayello, E. M. T., Boyce, A., Muckian, B., Ahmad, N., Hunter, C. J., Karver, M. R., Stupp, S. I., Sharma, A. K.. Advanced Therapeutics 2021, Accepted.

37. Superstructured Biomaterials Formed by Exchange Dynamics and Host-Guest Interactions in Supramolecular Polymers

#Edelbrock, A. N., #Clemons, T. D., Chin, S. M., Roan, J. J. W., Bruckner, E. P., Alvarez, Z., Edelbrock, J., Wek, K. S., Stupp, S. I. . Advanced Science 2021, Accepted.

36. Study of induced structural, optical and electrochemical properties of Poly (3-hexylthiophene) (P3HT), [6,6]-phenyl-C-61-butyric-acid-methyl-ester (PCBM) and their blend as an effect of graphene doping

Mahendia, P., Chauhan, G., Wadhwa, H., Kandhol, G., Mahendia, S., Srivastava, R., Sinha, O. P., Clemons, T. D., Kumar, S. Journal of Physics and Chemistry of Solids 2021, 148, 109644.

2020

35. Design of Materials with Supramolecular Polymers

Clemons, T. D., Stupp, S. I. Progress in Polymer Science 2020, 111, 101310.

34. Synthetic copolymer conjugates of docetaxel and in vitro assessment of anticancer efficacy

Evans, C. W., Edwards, S., Kretzmann, J. A., Nealon, G. L., Singh, R., Clemons, T. D., Norret, M., Boyer, C. A., Iyer, K. S. New Journal of Chemistry 2020, 44 (46), 20013-20020.

33. Proapoptotic Peptide Brush Polymer Nanoparticles via Photoinitiated Polymerization-Induced Self-Assembly

Sun, H., Cao, W., Zang, N., Clemons, T. D., Scheutz, G., Hu, Z., Thompson, M., Liang, Y., Vratsanos, M., Zhou, X., Choi, W., Sumerlin, B., Stupp, S., Gianneschi, N. Angewandte Chemie 2020, 59 (43), 19136-19142.

32. Transforming Growth Factor β-1 Binding by Peptide Amphiphile Hydrogels

Lewis, J., Freeman, R., Carrow, J., Clemons, T. D., Palmer, L., Stupp, S. ACS Biomaterials Science & Engineering 2020, 6 (8), 4551-4560.

31. Development of Optimized Tissue Factor-Targeted Peptide Amphiphile Nanofibers to Slow Non-Compressible Torso Hemorrhage

Klein, M. K.,  Kassam, H. A.,  Lee, R. H.,  Bergmeier, W.,  Peters, E. B.,  Gillis, D. C.,  Dandurand, B. R.,  Karver, M. R.,  Struble, M. D.,  Clemons, T. D.,  Palmer, L. C.,  Gavit, B.;  Pritts, T. A.,  Tsihlis, N. D.,  Stupp, S. I., Kibbe, M. R. ACS Nano 2020, 14 (6), 6649-6662.

30. Supramolecular and Hybrid Bonding Polymers

Stupp, S. I.,†  Clemons, T. D.,†  Carrow, J. K.,  Sai, H., Palmer, L. C. Israeli Journal of Chemistry 2020, 60, 1-9.

29. My Best Friend, Self-Doubt

Clemons, T. D. Matter 2020, 2 (1), 7-9.

28. Semiconductor Quantum Dots Are Efficient and Recyclable Photocatalysts for Aqueous PET-RAFT Polymerization

McClelland, K. P., Clemons, T, D., Stupp, S. I., Weiss, E, A., ACS Macro Letters 2020, 9, 7-13.

2019

27. Triple-hit therapeutic approach for triple negative breast cancers using docetaxel nanoparticles, EN1-iPeps and RGD peptides

Sorolla, A.,  Wang, E.,  Clemons, T. D.,  Evans, C. W.,  Plani-Lam, J. H. C.,  Golden, E.;  Dessauvagie, B.,  Redfern, A. D.,  Swaminathan-Iyer, K., Blancafort, P. Nanomedicine: Nanotechnology, Biology and Medicine 2019, 20, 102003.

26. Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis

Mansukhani, N., Peters, E. B., So, M. M., Albaghdadi, M. S., Wang, Z., Karver, M. R., Clemons, T. D., Laux, J. P., Tsihlis, N. D., Stupp, S. I., Kibbe, M. R. Macromolecular Bioscience 2019, 19 (6).

25. Book Chapter - Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications

Clemons, T. D.*,  Kerr, R., Joos, A. In Comprehensive Nanoscience and Nanotechnology, Second ed.; Andrews, D.;  Lipson, R.; Nann, T., Eds. Oxford: Academic Press: 2019; Vol. 3, pp 193-210.

24. Book Chapter - Designing online pre-laboratory activities for chemistry undergraduate laboratories

Spagnoli, D.,  Rummey, C.,  Man, N. Y. T.,  Wills, S. S., Clemons, T. D. In Teaching Chemistry in Higher Education: A Festschrift in Honour of Professor Tina Overton, Seery, M. K.; McDonnell, C., Eds. Creathach Press: Dublin, 2019; pp 315-332.

23. Introducing the First Year Laboratory to Undergraduate Chemistry Students with an Interactive 360 Degree Experience

Clemons, T. D., Fouche, L., Rummey, C., Lopez, R., Spagnoli, D. Journal of Chemical Education 2019, Accepted.

22. The Impact of Several Demographic Factors on Chemistry Laboratory Anxiety and Self-Efficacy in Students’ First Year of University

Rummey, C., Clemons, T. D.,* Spagnoli, D.* Student Success 2019, 10 (1), 87-98.

21. Novel hydrophilic copolymer-based nanoparticle enhances the therapeutic efficiency of Doxorubicin in cultured MCF-7 cells

Naidu, P., Norret, M., Dunlop, S. A., Fitzgerald, M., Clemons, T. D.*, Iyer, K. S.* , ACS Omega 2019, Accepted.

2018

20. Active or Passive Targeting of Nanoparticles Dictate Their Overall Therapeutic Efficacy

Clemons, T. D.*, Singh, R., Sorolla, A., Chaudhari, N., Hubbard, A., Iyer, K. S. Langmuir 2018, 34 (50), 15343-15349.

19. Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

Ho, D. W., Kretzmann, J. A., Norret, M., Toshniwal, P., Veder, J. P., Jiang, H. B., Guagliardo, P., Munshi, A. M., Chawla, R., Evans, C. W., Clemons, T. D., Nguyen, M., Kretzmann, A. L., Blythe, A. J., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J. A., Bond, C. S., Kilburn, M. R., Hurley, L. H., Smith, N. M., Iyer, K. S. Nature Nanotechnology 2018, 13 (12), 1148-+.

18. Coherency Image Analysis to Quantify Collagen Architecture: Implications in Scar Assessment 

Clemons., T. D.*, Bradshaw, M., Toshniwal, P., Chaudhari, N., Stevenson, A., Lynch, J., Fear, M., Wood, F. M., Iyer, K. S.* RSC Advances 2018, 8, 9661 – 9669.

2017

17. First Year Introductory Chemistry at the University of Western Australia: Reflections and Perceptions

Clemons, T. D., Bucat, R. B., Spagnoli, D. Australian Journal of Chemistry 2017, 71 (4), 203-211.

16. Sand training: Exercise-induced muscle damage and inflammation

Brown H, Dawson B, Binnie M, Pinnington H, Sim M, Clemons T, Peeling, P. European Journal of Sport Science. 2017, 17(6), 741-747.

15. Prepare, Do, Review: A model used to reduce the negative feelings towards laboratory classes in an introductory chemistry undergraduate unit

Spagnoli D,* Wong L, Maisey S, Clemons T.* Chemistry Education Research and Practice. 2017, 18, 26-44.

2016

14. Book Chapter - The Design and Testing of Multifunctional Nanoparticles for Drug Delivery Applications

Clemons, T. D.,  Viola, H.,  House, M.,  Hool, L., Iyer, S. In Nanomaterials - Science and Applications, Kane, D.;  Micolich, A.; Roger, P., Eds. Pan Stanford Publishing Pte. Ltd: Singapore, 2016; pp 1-47.

13. Manipulating Cellular Interactions of Poly(glycidyl methacrylate) Nanoparticles Using Mixed Polymer Brushes

Clemons T. D.*, Challenor M, Fitzgerald M, Dunlop S. A, Smith N. M, Iyer K. S.* . ACS Macro Letters. 2016, 5, 1132-1136.

12. Regulation of collagen expression using nanoparticle mediated inhibition of TGF-B activation

Li, B., Clemons, T. D., Agarwal, V., Kretzmann, J., Bradshaw, M., Toshniwal, P., Smith, M. N., Li, S., Fear, M., Wood, M. F., Iyer, K. S. New Journal of Chemistry. 2016, 40, 1091-1095.          

11. Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery

Agarwal, V., Toshniwal, P., Smith, E. N., Smith, M. N., Li, B., Clemons, T. D., Byrne, T. L., Kakulas, F., Wood, M. F., Fear, M., Corry, B., Iyer, K. S. Chemical Communications 2016, 52, 327-330.

10. A comparison of haemolytic responses in fore-foot and rear-foot distance runners

Caulfield S, McDonald K. A, Dawson B, Stearne S. M, Green B. A, Rubenson J, Clemons T. D., Peeling P. Journal of Sports Sciences. 2016, 34, 1485-1490.

2015

9. RNAi using c-Myc-Conjugated Non-Viral Macromolecular Vector Suppresses Breast and Colorectal Cancer Models

Tangudu, N., Verma, V., Clemons, T., Beevi, S., Hay, T., Mahidhara, G., Raja, M., Nair, R., Smith, N., Alexander, L., Patel, A., Jose, J., Zdyrko, B., Bourdoncle, A., Luzinov, I., Clarke, A., Iyer, S., Kumar, L., Molecular Cancer Therapeutics. 2015, 14, 1259.

8. Manipulating Directional Cell Motility Using Intracellular Superparamagnetic Nanoparticles

Bradshaw M, Clemons T, Ho D, Gutierrez L, Lazaro F, House M, St-Pierre T, Fear M, Wood F, Iyer S. . Nanoscale. 2015, 7, 4884.

7. Nanoparticle-Mediated Dual Delivery of an Antioxidant and a Peptide against the L‐Type Ca2+ Channel Enables Simultaneous Reduction of Cardiac Ischemia-Reperfusion Injury

Hardy N, Viola H, Johnstone V, Clemons T, Cserne Szappanos H, Singh R, Smith N, Iyer S, Hool L. ACS Nano. 2015, 9, 279.

2013

6. An Improved Assay for the Spectrophotometric Determination of Chondroitinase ABC Activity

Clemons, T., Fitzgerald, M., Dunlop, S., Harvey, A., Iyer, K. S., Stubbs, K., New Journal of Chemistry 2013, 37, 1944.

5. Examining Efficacy of “TAT-less” Delivery of a Peptide against the L-Type Calcium Channel in Cardiac Ischemia-Reperfusion Injury

Clemons, T., Viola, H., House, M., Iyer, K. S., Hool, L. ACS Nano, 2013, 7, 2212.

2012

4. Multimodal and Multifunctional Stealth Polymer Nanospheres for Sustained Drug Delivery

Evans, C., Latter, M., Ho, D., Peerzade, S., Clemons, T., Fitzgerald, M., Dunlop, S., Iyer, S. New Journal of Chemistry 2012, 36, 1457.

3. In vivo Imaging and Biodistribution of Multimodal Polymeric Nanoparticles Delivered to the Central Nervous System

Harrison, J., Bartlett, C., Cowin, G., Nicholls, P., Evans, C., Clemons, T., Zdyrko, B., Luzinov, I., Harvey, A., Iyer k. S., Dunlop, S., Fitzgerald, M. Small, 2012, 8, 1579.

2011

2. Multifunctional Nanoadditives for the Thermodynamic and Kinetic Stabilization of Enzymes

Clemons, T., Evans, C., Zdyrko, B., Luzinov, I., Fitzgerald, M., Dunlop, S., Harvey, A., Iyer, S., Stubbs, K. Nanoscale 2011, 3, 4085.

1. Multimodal Analysis of PEI-Mediated Endocytosis of Nanoparticles in Neural Cells

Evans, C. W., Fitzgerald, M., Clemons, T. D., House, M. J., Padman, B. S., Shaw, J. A., Saunders, M., Harvey, A. R., Zdyrko, B., Luzinov, I., Silva, G. A., Dunlop, S. A., Iyer, K. S. ACS Nano 2011, 5, 8640.